Migraine and Pain Relief IV Ingredients Lidocaine Magnesium Sulfate Calcium Chloride B-Complex (w/Riboflavin) Sodium Bicarbonate Methylcobalamin (B12) Ketorolac (Toradol) Saline Indications Migraine Relief IV Therapy can be supportive in many conditions, but the following have been found to have the most support: Migraines Muscle spasms Chronic and Acute Pain Asthma Precautions People may experience a feeling of warmth or mild discomfort when receiving an IV. It is common for patients to taste some of the vitamins, but for those who do not taste them, they are still getting the nutrition. Rare complications that can occur during intravenous therapies include phlebitis (inflammation of the vein) and fluid infiltration (leaking of fluid into the surrounding tissues). Greater than 20 million Americans suffer from migraines, which is a vascular headache that may cause a disabling cascade of symptoms. There is no doubt that lifestyle modifications can reduce the severity and frequency of migraines, especially sleep and diet. When considering diet there are some specific nutrients that can have major impact on migraines. Research has found that magnesium levels effect the chemicals Page 1 NUTRIENT IV THERAPY Migraine Relief IV serotonin, nitric oxide, and NMDA (N-methyl-Daspartic acid), which are associated with blood vessel relaxation and suspected to have a strong association with migraines. Magnesium Chloride Magnesium plays an important role in many of the body’s enzymatic reactions, in neurochemical transmission, and muscle contraction and relaxation. It is responsible for over 300 essential metabolic reactions in the body. It is required for synthesizing proteins in the mitochondria, and for generating energy in most of the body’s basic cellular reactions. Magnesium acts on the vascular system to produce vasodilation the relaxation of blood vessel walls increasing blood flow, which can help with lowering blood pressure and also preventing and treating migraine headaches. Methylcobalamin (B12) The natural form of B12 (methylcobalamin) is better absorbed than Cyanobalamin and has been used to treat diseases such as pernicious anemia, and diabetic and peripheral neuropathy. Vitamin B12 is an essential component for proper digestion and absorption of foods and for normal metabolism of carbohydrates, and fat. It aids in maintaining healthy nerve cells and red blood cells and is needed to make DNA. Vitamin B12 is also involved in homocysteine metabolism and plays a critical role in proper energy metabolism, immune function, and nerve function. Riboflavin Riboflavin (vitamin B2) works with the other B vitamins and is important for red blood cell production and helps in releasing energy from carbohydrates. This is important for the brain to utilize the maximum amounts of energy during the time of a migraine attack. Page 2 NUTRIENT IV THERAPY Migraine Relief IV Lidocaine Lidocaine injection is a local anesthetic (numbing medication). It works by blocking nerve signals in your body and is used to help reduce pain or discomfort. Ketorolac Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) and is used for the short term treatment of moderate pain and inflammation. Reducing pain and inflammation such as headaches will help you recover more comfortably so that you can return to your normal daily activities.